Ketamine infusion therapy for PTSD

Ketamine Therapy PTSD

For individuals whose PTSD symptoms persist despite traditional treatments, ketamine infusion therapy offers a promising alternative. Administered in a clinical setting under physician supervision, this emerging treatment may rapidly reduce hyperarousal, intrusive memories, and distress where SSRIs and talk therapies have fallen short. Learn if ketamine therapy could be part of your recovery path.

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Ketamine Therapy PTSD

Ketamine Infusion Therapy for PTSD

PTSD or Post Traumatic Stress Disorder occurs after significant trauma such as being in a war zone, abuse or rape. Any life-threatening situation with great fear can imprint this trauma on an individual. They continue to suffer this stressful condition. Symptoms such as relieving the event, feeling hyperarousal (keyed up and on edge) as well as avoiding certain triggering situations as well as having many negative feelings. It is very difficult for those that suffer from PTSD. An alternative treatment is ketamine infusion therapy for PTSD.

The standard treatment medications are serotonin re-uptake inhibitors (SSRIs) and or talk therapies such as “Trauma Focused Psychotherapy”. Other therapies such as “Eye Movement Desensitization and Reprocessing” are also used. These are sometimes used alone or in combination with each other. Traditional therapies such as these are sometimes successful and may help the individual. However, sometimes they are not, and the PTSD patient will continue to suffer. Of all of these, the most successful treatment appears to be “Cognitive Behavioral Therapy”. This enjoys some success and should be tried before moving into a new treatment for PTSD. Yet once these therapies fail, one may want to consider alternate therapies such as those found at our clinic.

A new treatment is emerging using Ketamine infusion for PTSD.

Given in small doses by intravenous administration has been found in small-scale studies to help PTSD. It is believed to work in an unusual fashion. What is believed is that by rerouting nerve endings this creates new synaptic connections. A synapse is how nerves communicate. Thus, in the brain, these brain cells learn new ways to communicate breaking the old habits which produce PTSD. If this is true, this may one way to change the brain.

One such study was a “proof of concept study” was carried out and the results of Ketamine infusion was associated with a significant and rapid reduction in PTSD symptoms severity, compared with midazolam, when assessed 24 hours after infusion (mean difference in Impact of Event Scale-Revised score was 12.7 [95% CI, 2.5-22.8]; P = 0.02).

However, it should be cautioned that not every patient will respond favorably and this certainly is not standard care for PTSD. One should have tried the traditional and more accepted approaches to PTSD treatment. One should also be working with a mental health professional before coming to our Ketamine Clinic.

Contact the Ketamine Clinic of Hawaii

If you have questions about ketamine infusion therapy or would like to request more information about evaluation, eligibility, or treatment options, please complete the form below. A member of our clinical team will review your message and respond as appropriate. Submission of this form does not establish a physician–patient relationship.

Decades of Clinical Experience With Ketamine

Ketamine is not new to us. Long before ketamine entered broader mental health care, it was a routine and trusted medication in surgical medicine. Our physicians have used ketamine safely for decades in operating rooms, including plastic and reconstructive surgery, where precise dosing, monitoring, and patient stability are critical.

Hawaii's First Ketamine Clinic

We were the first ketamine clinic in Hawaii and among the earliest in the United States to offer ketamine therapy in a dedicated clinical setting. That history matters. Our approach is grounded in real-world medical use, not trends or experimentation. Every protocol we use today is informed by years of surgical experience, clinical judgment, and patient safety standards developed in hospital environments.

This foundation distinguishes our care. Ketamine therapy here reflects long-standing medical practice, applied carefully to modern therapeutic use.

Ketamine Clinic Hours

Monday 9:00AM – 4:30PM
Tuesday 9:00AM – 4:30PM
Wednesday 9:00AM – 4:30PM
Thursday 9:00AM – 4:30PM
Friday 9:00AM – 4:30PM
Saturday 9:00AM – 1:00PM
Sunday Closed

If your suffering from chronic pain, severe depression, PTSD or addiction and your interested in Ketamine infusion treatment, give us a call or email us!

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Our Location

Ketamine Clinic of Hawaii
677 Ala Moana Blvd Suite 1023
Honolulu, Hawaii 96813
Phone: 808-945-5433