ketamine-chronic-pain

Ketamine Therapy Chronic Pain

Clinically supervised ketamine therapy addressing chronic pain by modulating central pain pathways and neuroplastic responses, offering relief when conventional pain treatments, medications, or interventions have failed to provide durable improvement.

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Ketamine Therapy Chronic Pain

Ketamine Therapy Chronic Pain

Ketamine is becoming a new accepted treatment for chronic pain patients. This new treatment shows promise and is being used by the pain specialist. Many pain specialists who treat conditions such as Fibromyalgia, CRPS/RSD and the like become frustrated as do their patients. Previously these conditions were very refractory to traditional pain medications over the long term. In many of these cases, there is simply no cure. Now with Ketamine, there is some light appearing in this dark tunnel!

Ketamine Infusion Therapy for Chronic Pain

Pain syndromes, RSD, CRPS, Fibromyalgia, these type of pains may no longer respond to traditional treatments but may respond well to Ketamine infusions. This offers some hope to many who have suffered, without the risk of being addicted to narcotics.

How does Ketamine work for pain?

The scientific studies are small and it is not standard therapy. Exactly, how this success occurs is speculative. Ketamine chronic pain therapy appears to reset the pain receptors and changing some of the neurochemistry on a long-term basis.

Glutamine, an amino acid is found in “connections” between the brain cells. These brain cells are called neurons. The connection between these cells is called a synapse. These synapses are responsible for transmitting signals and they can become rather “out of kilter” or the wires are crossed in chronic pain and depression syndromes. This mixes up, at that cell level may cause a person to be in pain for no apparent reason long after the source was identified and cured. In other words, chronic pain patients may have their “wires” crossed so to speak. The brain may recognize this as a normal state so does nothing to change. Yet, ask any chronic pain patient if they like this “normal”. There is nothing normal about chronic pain.

What Ketamine will do is block some of the neurochemicals such as NMDA receptors found in the synaptic connecting elements. Thus, by blocking NMDA, another neurotransmitter may be increased to a higher level available to the brain tissues. This increase in neuro-active substances or decrease may be at the heart of pain and reversal of pain. This is very complex, but we can visualize it as an orchestra with many different instruments all playing out of order. In turn, Ketamine may eliminate pain and depression by properly arranging the orchestra instruments.

There is yet another theory which accounts for the long-term pain-relieving effects of Ketamine. Although speculative at this point, Ketamine may reset these pain receptors meaning it changes them on a more long-term basis instead of just during the time of the Ketamine infusion. That means once your unplugged and are no longer receiving the infusion, the relief may continue for days, weeks or perhaps months. Once the wires are uncrossed so the speak, the patient feels relief on a long-term basis. So, indeed Ketamine may uncross the wires!

Contact us, if you are interested in Ketamine Therapy

If your traditional treatment has failed for pain syndromes, call our office to set up an appointment. We are located in Honolulu, Hawaii at the Water Front Plaza, formally known as Restaurant Row.

The FDA has not approved Ketamine as an approved treatment for chronic pain. It is an off-label use at this time. However, Ketamine is approved by the FDA for anesthetic purposes and acute pain.

Contact the Ketamine Clinic of Hawaii

If you have questions about ketamine infusion therapy or would like to request more information about evaluation, eligibility, or treatment options, please complete the form below. A member of our clinical team will review your message and respond as appropriate. Submission of this form does not establish a physician–patient relationship.

Decades of Clinical Experience With Ketamine

Ketamine is not new to us. Long before ketamine entered broader mental health care, it was a routine and trusted medication in surgical medicine. Our physicians have used ketamine safely for decades in operating rooms, including plastic and reconstructive surgery, where precise dosing, monitoring, and patient stability are critical.

Hawaii's First Ketamine Clinic

We were the first ketamine clinic in Hawaii and among the earliest in the United States to offer ketamine therapy in a dedicated clinical setting. That history matters. Our approach is grounded in real-world medical use, not trends or experimentation. Every protocol we use today is informed by years of surgical experience, clinical judgment, and patient safety standards developed in hospital environments.

This foundation distinguishes our care. Ketamine therapy here reflects long-standing medical practice, applied carefully to modern therapeutic use.

Ketamine Clinic Hours

Monday 9:00AM – 4:30PM
Tuesday 9:00AM – 4:30PM
Wednesday 9:00AM – 4:30PM
Thursday 9:00AM – 4:30PM
Friday 9:00AM – 4:30PM
Saturday 9:00AM – 1:00PM
Sunday Closed

If your suffering from chronic pain, severe depression, PTSD or addiction and your interested in Ketamine infusion treatment, give us a call or email us!

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Our Location

Ketamine Clinic of Hawaii
677 Ala Moana Blvd Suite 1023
Honolulu, Hawaii 96813
Phone: 808-945-5433